// Precision Drug Delivery

Molecular
Formulation
at the Tip of
a Needle

We take your molecule and engineer the patch.
Next-generation dissolving microneedle arrays — engineered for pain-free administration, precise drug loading and seamless patient experience

Microneedle Array
Microneedle Array
// Core Technology

Precision
at Every Scale

Each array contains dozens of micro-sharp tips, engineered with sub-micron accuracy for consistent transdermal delivery.

// Polymer Engineering

Dissolving
by Design

Customized polymer matrices encapsulate the active molecule — releasing it in a controlled, reproducible manner upon skin contact

// Molecular Formulation

Formulated
for the Patient

Making effective therapies more accessible — through innovation that puts the patient first.

A Growing Global
Imperative

0$
Global Market Size 2024
Microneedle Drug Delivery Systems
Grand View Research, Microneedle Drug Delivery Systems Market Report, 2024
0
Annual Market Growth
CAGR 2025–2030
Grand View Research, Microneedle Drug Delivery Systems Market Report, 2024
0$
Projected Market 2030
Driven by dissolving microneedle adoption
Grand View Research, Microneedle Drug Delivery Systems Market Report, 2024
0
Adults with Needle Anxiety
A core barrier to treatment compliance
Harvard Health Blog — Terrified of needles? That can affect your health, 2021
// Core Technology
Microneedle Array Close-up
Array Resolution
Dissolving Polymer Matrix

Engineered at the
Molecular Scale

Our microneedle arrays are fabricated with sub-micron precision, embedding active pharmaceutical ingredients directly within a biocompatible polymer matrix. Each needle tip is architected to dissolve at a controlled rate — governed by molecular interactions between drug, excipient, and tissue

Polymer Matrix Engineering
Customized polymer matrices are optimized per drug molecule — tuning solubility, diffusion kinetics and degradation profiles at the nanoscale.
Transdermal Penetration Control
Needle geometry and aspect ratios are computationally derived to enable precise, minimally invasive transdermal drug delivery — ensuring controlled and reproducible permeation through the skin
Scalable GMP Fabrication
Envisioning a scalable process, we are developing robust manufacturing workflows designed to transition from laboratory-scale fabrication to industrial production — ensuring consistent array quality, geometric precision and drug loading uniformity across every batch.

Where Deep Learning
Meets Molecular Chemistry

BIOAXXENT's proprietary formulation approach maps the multi-dimensional interaction space between active molecules, excipients, and biological membranes — accelerating formulation design from months to days.

01
Molecular Interaction Modelling
Graph neural networks encode the full interaction landscape of drug-excipient pairs — predicting hydrogen bonding, hydrophobic contacts, and crystallization propensity before any experiment is run
GNN · MD Simulation
02
Predictive Formulation Design
Bayesian optimization loops integrate in-silico predictions with high-throughput experimental data, converging on optimal excipient ratios and processing conditions with minimal wet-lab iterations
Bayesian Opt · HTS
03
Release Kinetics Prediction
In vitro screening tools enable early-stage prediction of drug release behavior — guiding formulation decisions before costly in vivo studies. Physics-informed neural networks further simulate diffusion-reaction dynamics within the dissolving matrix, accelerating release profile prediction
PINN · PK Modelling
CH₃ H OH φ H-bond H-bond H-bond N N N N O O O Ala Gly Ser Phe peptide peptide peptide

From Molecular Simulation
to Clinical Formulation

Our advanced molecular screening computes free energies of binding, diffusion coefficients, and phase stability across thousands of candidate formulations simultaneously — reducing experimental waste by over 70%.

Molecular Dynamics Free Energy Perturbation Graph Neural Networks Bayesian Optimization
Dissolving Microneedle Array Microneedle Patch
Dissolving Array

Engineered with
Uncompromising Precision

Each dissolving microneedle array is precision-engineered with dozens of sharp polymer tips — designed to penetrate the outermost skin layer painlessly and dissolve completely on contact, releasing the encapsulated active molecule with controlled, reproducible kinetics.

DissolvingMatrix Type
Sub-mmNeedle Height
Pain-FreeApplication

A Fingertip of
Molecular Science

The complete patch platform — smaller than a postage stamp — integrates the full formulation stack: substrate, drug-loaded polymer matrix, and release layer. Engineered for self-administration, room-temperature stability and seamless integration into patients' daily lives

CompactForm Factor
Self-ApplyAdministration
StableRoom Temperature

From Molecule to
Market-Ready Patch

1
Molecular Screening
Computational and experimental screening maps drug-excipient interactions across thousands of combinations — rapidly identifying the most promising formulation candidates
2
In-Silico Formulation
Molecular modelling and simulation predict solubility, stability and release profiles — reducing experimental iterations early in development
3
Rapid Prototyping
Advanced fabrication techniques allow for fast turnaround of prototype arrays — enabling quick design iterations and early proof-of-concept
4
Analytics & QC
High-resolution microscopy and spectroscopic methods validate drug distribution and array integrity at every stage of development
5
Scale-Up & GMP
Robust manufacturing processes ensure consistent quality and reproducibility — designed to scale from lab to clinical and commercial supply

Treatment,
Reimagined

Nobody chooses to be sick. Nobody should fear their treatment. At BIOAXXENT, we believe that the science of drug delivery has a human obligation — to make medicine more accessible, more comfortable, and more effective for every patient

01
// Fear Shouldn't Be a Barrier

Fear shouldn't stand between
a patient and their medicine

1 in 4 adults experiences needle anxiety. For patients managing chronic conditions — diabetes, hormone therapy, immunology — requiring regular injections, this creates a real and measurable barrier to treatment compliance. BIOAXXENT's dissolving microneedle arrays make administration painless, stress-free and self-manageable at home — removing fear from the equation entirely

Pain-Free Administration
02
// Beyond the Gut

Not every molecule survives
the journey through the gut

Many therapeutic peptides, proteins and biologics are destroyed by stomach acid before they ever reach the bloodstream. Transdermal delivery through the skin bypasses this entirely — opening a new class of molecules to non-injectable, patient-friendly administration. What previously required a clinic visit and a syringe can now be applied in seconds at home

New Therapeutic Frontiers
03
// Engineered for Each Molecule

A patch smaller than a postage stamp —
a difference measured in lives

Through advanced polymer formulation and molecular screening, BIOAXXENT engineers each microneedle array specifically for the molecule it carries — optimising release kinetics, stability and skin permeation. The result is a delivery system that is gentler, simpler and more accessible — turning complex pharmaceutical science into a seamless patient experience

Precision Formulation
"We formulate for the molecule.
We design for the patient."

BIOAXXENT GmbH

BIOAXXENT GmbH

Bahnhofstr. 18–20
57518 Betzdorf
Germany


Contact

Phone: +49 175 5225532
E-Mail: info@bioaxxent.com
Web: www.bioaxxent.com


Geschäftsführer

Dr. Stefan Henke


Handelsregister

Amtsgericht Montabaur, HRB 30638
Rechtsform: Gesellschaft mit beschränkter Haftung


Umsatzsteuer

Umsatzsteuer-ID: 02/660/15938

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Bahnhofstr. 18–20
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Deutschland
E-Mail: info@bioaxxent.com

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Last updated: May 2026